'UFC 166: Velasquez vs. dos Santos III' lineup set, flyweights on main card

In addition to a major heavyweight championship trilogy, October’s UFC 166 event features 13 total bouts, a preliminary card full of familiar names, and a main card that kicks off with a pair of flyweights.

UFC 166 takes place Oct. 19 at Houston’s Toyota Center. The main card airs on pay-per-view following prelims on FOX Sports 1 and Facebook.

The big men take center stage at the fall event. In the headliner, heavyweight champion Cain Velasquez (12-1 MMA, 10-1 UFC) and former titleholder Junior dos Santos (16-2 MMA, 10-1 UFC) meet in a rubber match. In the co-headliner, Daniel Cormier (12-0 MMA, 1-0 UFC) likely fights at heavyweight for the final time when he takes on Roy Nelson (19-8 MMA, 6-4 UFC).

Additionally, rather than a usual spot buried on the preliminary card, flyweights kick off the main card as John Dodson (14-6 MMA, 3-1 UFC) welcomes Darrell Montague (13-2 MMA, 0-0 UFC) to the organization.

The prelims, meanwhile, feature a host of notables, including former Strikeforce champions Luke Rockhold, Nate Marquardt and Sarah Kaufman.

The official UFC 166 card includes:

MAIN CARD (Pay-per-view, 10 p.m. ET)

• Cain Velasquez vs. Junior dos Santos – for heavyweight title
• Daniel Cormier vs. Roy Nelson
• Gilbert Melendez vs. Diego Sanchez
• Gabriel Gonzaga vs. Shawn Jordan
• John Dodson vs. Darrell Montague

PRELIMINARY CARD (FOX Sports 1, 8 p.m. ET)

• Tim Boetsch vs. Luke Rockhold
• Hector Lombard vs. Nate Marquardt
• Jessica Eye vs. Sarah Kaufman
• K.J. Noons vs. George Sotiropoulos

PRELIMINARY CARD (Facebook, 6 p.m. ET)

• Adlan Amagov vs. T.J. Waldburger
• Tony Ferguson vs. Mike Rio
• Charles Oliveira vs. Estevan Payan
• Matt Grice vs. Jeremy Larsen

For more on UFC 166, check out the UFC Rumors section of the site.

(Pictured: Cain Velasquez)